Effects of an Exercise Program on Preserving Function and Participation in People with Multiple Sclerosis

Principal Investigator: James Bowen, MD

Exercise has the potential to positively influence a number of aspects of MS. Previous studies have shown that exercise results in widespread benefits for those with MS, including decreased fatigue, pain, and depression, increased strength and cardiovascular fitness, and improved quality of life. However, concerns about fatigue and mobility frequently prevent individuals from utilizing this important rehabilitative tool. It may also be difficult to begin or maintain these healthy habits without support.

The specific aim of this study was to determine whether early intervention through physical therapy and a home exercise program would decrease disability in people with MS by improving physical function, decreasing pain, and improving participation in life activities.

Data for this study has been collected and is currently being analyzed, with results to be published shortly. Preliminary outcomes and results from this study include the following:

Published abstracts:

1. Cline, Melissa J; LaRotonda, Chiara J; Wadhwani, Rohini V; Bombardier, Charles H; Ehde, Dawn; Kraft, George H; Bowen, James D. (2006) Predictors of Adherence to Exercise Goals in Patients with Multiple Sclerosis. International Journal of MS Care, 8 (2), 50.
• View the Abstract (Page 50).
2. LaRotonda, Chiara J; Wadhwani, Rohini V; Cline, Melissa J; Bowen, J; Bombardier, C; Ehde, D; Kraft, G. Barriers to increased physical activity in ambulatory MS sample. International Journal of MS Care, 8(2), 59-60.
• View the Abstract (Page 59-60).
3. Wadhwani, Rohini V; Cline, Melissa J; LaRotonda, Chiara J; JD, Bowen; DM, Ehde; GH, Kraft. Adherence to CDC/ACSM physical activity guidelines in a community sample of persons with multiple sclerosis. International Journal of MS Care, 8(2), 42-43.
• View the Abstract (Page 42-43).
4. Barnes, R; Kraft, G; Wadhwani, R; Ciol, M; Bombardier, CH; J, Bowen. (2007) Role of Historic Leisure Activity in Starting a Home Exercise Program. International Journal of MS Care, 9 (2), 50.
• View the Abstract (Page 50).
5. Bowen, J; Madrone, K; Wight, K; Wadhwani, R; Bombardier, C; Ehde, D; Kraft, G. (2008) Motiviational counseling and strengthening exercises in patients with multiple sclerosis. International Journal of MS Care, 10 (S1), 11.
• View the Abstract (Page 11).