Comparing a self report questionnaire with physician assessment for determining multiple sclerosis clinical disease course: a validation study.

TitleComparing a self report questionnaire with physician assessment for determining multiple sclerosis clinical disease course: a validation study.
Publication TypeJournal Article
2007
AuthorsBamer AM, Cetin K, Amtmann D, Bowen JD, Johnson KL
JournalMultiple Sclerosis
Volume13
Issue8
Pagination1033-7
Date Published2007 Sep
ISSN1352-4585
Disease Progression, Humans, Multiple Sclerosis, Outpatients, Physicians, Questionnaires, Reproducibility of Results

Determining multiple sclerosis (MS) clinical course is important in research and clinical practice. However, many patients do not know their clinical course, limiting the option to use self-report in research studies including surveys. In order to address this, we developed a self-report item to be used in self-administered mailed surveys displaying graphically the courses of MS. The validity of this item was then evaluated by comparing physician-assessed disease clinical course to patient response on the self-report item on 94 of 99 consecutive patients seen in an MS specialty clinic. Kappa statistics were calculated comparing self-assessed versus physician-assessed MS clinical course for the four common MS clinical courses (kappa=0.45) and for relapsing remitting versus other courses (kappa=0.62) indicating substantial agreement. Subsequent administration of the item by mail to 1371 individuals with MS in Washington and Montana determined that while most individuals responded as intended to the item, persons with less than a high school education (P=0.009) or over the age of 60 ( P = 0.002) were significantly more likely to leave the item blank. It appears that this item may be used to obtain a rough estimate of MS clinical course in research using self-report surveys where physician assessments are impractical.

10.1177/1352458507077624
Alternate JournalMult. Scler.

Sign up!

We'll send you a regular email newsletter keeping you informed of what's happening at the MSRRTC.

Send us a message to sign-up. 

Studies Seeking Volunteers:

Currently there are no MSRRTC studies seeking volunteers.

Please check the Dept. of Rehabilitation Medicine's website for other studies on Multiple Sclerosis.