Hypersexuality Associated with a Multiple Sclerosis Exacerbation.

TitleHypersexuality Associated with a Multiple Sclerosis Exacerbation.
Publication TypeJournal Article
AuthorsSeverson BJ, Bowen JD, Yang CC, Haupt BA, Toshima MT
JournalInternational Journal of MS Care

Background: A 51-year-old female presented to the Western Multiple Sclerosis Center with a new complaint of hypersexuality atypical of her. The problem began 10 days earlier after the patient heard a “loud crashing sound” inside her head, like a “gunshot.” Following this incident, the patient’s sexual desire heightened to the degree that she wanted to “drag someone off the street for sex” at all hours of the day and night. The patient said she was happily married and this new behavior was frightening. It also annoyed her husband. After a few days of frequent sex, he was unable to keep up with his wife’s demands despite obtaining a new prescription for Viagra. Upon further questioning, the patient recalled another incident of hypersexuality occurring two years earlier, which was also preceded by hearing a loud gunshot sound inside her head. At that time the problem was less severe and lasted approximately seven days before spontaneously resolving. Methods: Diagnostic work-up includes history and physical exam, consulting with MS specialists and additional health care providers, ordering a brain magnetic resonance imaging (MRI) scan, drawing labs (including hormone levels), and treating with pulse steroids if warranted. Steroids were delivered and resulted in a significant reduction in symptoms. Unfortunately, the problem returned soon after the steroid treatment was completed. The plan is to repeat the brain MRI scan, with triple strength gadolinium, to more specifically assess for MS disease activity, and repeat pulse steroids if necessary. Evaluation: Recurrent hypersexuality in a multiple sclerosis patient responsive to steroids. Diagnostic work-up in progress.


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